Infusion is a chemical process that uses botanicals (typically dried herbs, flowers or berries) that are volatile and release their active ingredients readily in water, oil, or alcohol. In this process, a liquid is typically boiled (or brought to another appropriate temperature) and poured over the herb. After the herb has been allowed to steep in the liquid for an appropriate period of time, it is removed (possibly by straining) leaving an infusion. Unless the infusion is to be consumed immediately, it is bottled and refrigerated for future use.
The amount of time the herbs are left in the liquid depends on the kind of infusion. Infusion times can range from seconds (for some kinds of Chinese tea) to hours, days, or months (for liqueurs like Sloe Gin).
Home infusion therapy involves the intravenous or subcutaneous administration of drugs or biologicals to an individual at home. The components needed to perform home infusion include the drug (for example, antivirals, immune globulin), equipment (for example, a pump), and supplies (for example, tubing and catheters). Likewise, nursing services are necessary to train and educate the patient and caregivers on the safe administration of infusion drugs in the home. Visiting nurses often play a large role in home infusion. Nurses typically train the patient or caregiver to self-administer the drug, educate on side effects and goals of therapy, and visit periodically to assess the infusion site and provide dressing changes. The home infusion process typically requires coordination among multiple entities, including patients, physicians, hospital discharge planners, health plans, home infusion pharmacies, and, if applicable, home health agencies.
For questions about home infusion therapy payment policy, please view the Home Infusion Therapy Services Benefit Beginning 2021, Frequently Asked Questions (PDF) document or send your inquiry via email to: HomeInfusionPolicy@cms.hhs.gov.
In general, an infusion pump is operated by a trained user, who programs the rate and duration of fluid delivery through a built-in software interface. Infusion pumps offer significant advantages over manual administration of fluids, including the ability to deliver fluids in very small volumes, and the ability to deliver fluids at precisely programmed rates or automated intervals. They can deliver nutrients or medications, such as insulin or other hormones, antibiotics, chemotherapy drugs, and pain relievers.
Epstein-Barr virus (EBV) causes potentially lethal immunoblastic lymphoma in up to 25% of children receiving bone marrow transplants from unrelated or HLA-mismatched donors. Because this complication appears to stem from a deficiency of EBV-specific cytotoxic T cells, we assessed the safety and efficacy of donor-derived polyclonal (CD4(+) and CD8(+)) T-cell lines as immunoprophylaxis and treatment for EBV-related lymphoma. Thirty-nine patients considered to be at high risk for EBV-induced lymphoma each received 2 to 4 intravenous infusions of donor-derived EBV-specific T lymphocytes, after they had received T-cell-depleted bone marrow from HLA-matched unrelated donors (n = 33) or mismatched family members (n = 6). The immunologic effects of this therapy were monitored during and after the infusions. Infused cells were identified by detection of the neo marker gene. EBV-specific T cells bearing the neo marker were identified in all but 1 of the patients. Serial analysis of DNA detected the marker gene for as long as 18 weeks in unmanipulated peripheral blood mononuclear cells and for as long as 38 months in regenerated lines of EBV-specific cytotoxic T cells. Six patients (15.5%) had greatly increased amounts of EBV-DNA on study entry (>2, 000 genome copies/10(6) mononuclear cells), indicating uncontrolled EBV replication, a complication that has had a high correlation with subsequent development of overt lymphoma. All of these patients showed 2 to 4 log decreases in viral DNA levels within 2 to 3 weeks after infusion and none developed lymphoma, confirming the antiviral activity of the donor-derived cells. There were no toxic effects that could be attributed to prophylactic T-cell therapy. Two additional patients who did not receive prophylaxis and developed overt immunoblastic lymphoma responded fully to T-cell infusion. Polyclonal donor-derived T-cell lines specific for EBV proteins can thus be used safely to prevent EBV-related immunoblastic lymphoma after allogeneic marrow transplantation and may also be effective in the treatment of established disease.
FDA is issuing this guidance to provide a policy to help expand the availability and remote capabilities of infusion pumps and their accessories for health care professionals during the COVID-19 pandemic.
Receiving medication by infusion therapy is a method of administering a drug by a needle or catheter inserted into a vein. In the hospital, IV therapy is commonly used when a patient cannot take medications orally or for treatments where an intravenous route is more effective. Some examples are to treat serous infections, cancer, dehydration, gastrointestinal diseases, or autoimmune diseases. Infusion therapy may need to be continued after discharge or even started as an outpatient to treat certain disease and infections.
The expense of infusion therapy can be an obstacle for some patients. Receiving infusions in the hospital typically can cost up to twice as much as therapy in an outpatient office infusion center. For patients who require multiple treatments over an extended period, their best option may be to have this performed at specialized facilities such as infusion centers. These centers are generally more comfortable and private than the hospital and are frequently less expensive.
Less common is an infusion reaction. For some people, the drugs administered can react with the skin. This is more likely to occur within the first two hours of administration but can be seen up to 24 hours later as well. These symptoms can include:
Infectious Disease Associates of Tampa Bay has a team of physicians, a highly skilled nursing staff, and two state-of-the-art ambulatory care facilities to offer our community the highest quality outpatient infusion services available. Our goal is to provide efficient, friendly, and comprehensive care under direct physician supervision at our two convenient locations.
Infusion Therapy may be needed as part of the discharge plan for many hospitalized patients from different surgical and medical services. Additionally, outpatient infusion services may prevent a hospital admission or readmission. For more information, call us at (813) 251-8444.
Long-term health issues are stressful and expensive. During the past few years, in attempts to lower costs, insurance companies have forced patients who need infusion therapy to seek treatment in outpatient clinics. This can become even more overwhelming for patients who already have to deal with the less than ideal reality of having a needle stuck in them on a regular basis.
Our clinic provides infusion therapy for illnesses that require the administration of medications through a needle or catheter. If you have a prescription from your physician, we offer treatment for the following conditions:
If you have chemotherapy by infusion, the medication is delivered to your bloodstream through a needle in a vein from your arm or a central line. You might also receive supportive medications or treatments (such as hydration) by infusion.
What to Expect at Your First Infusion Appointment It is normal for patients to feel a little nervous about starting infusion treatment, also known as chemotherapy or chemo. This video walks you through what to expect on your first day of treatment.
Our mission at the Mount Sinai Morningside Infusion Suite is to deliver high-quality, comprehensive medical care, while maintaining optimal quality of life. Our experienced oncologists and hematologists treat a wide range of cancer and blood disorders using the latest treatment protocols. We provide individualized care in an intimate boutique setting on the Upper West Side. As an extension of the highly regarded Tisch Cancer Institute at The Mount Sinai Hospital, the Mount Sinai Morningside Infusion Suite offers outstanding infusion services in a friendly and caring environment, as reflected in our high patient satisfaction scores.
In addition to chemotherapy, we provide intravenous medications for benign hematologic conditions, therapeutic infusions for rheumatologic disorders such as rheumatoid arthritis, and blood transfusions. Treatment is administered by highly trained, compassionate nurses.
We understand how overwhelming it can be for those being treated for these illnesses. Our team of physician specialists and skilled infusion nurses partners closely with patients and their families to allay their concerns and treats them with dignity, respect, and consideration. Patients and their loved ones find that our medical expertise and compassionate, patient-centered approach make the Mount Sinai Morningside Infusion Suite a strong and able ally in their fight against formidable illness while giving them peace of mind.
To ease the burden of travel for patients in need of oncology or infusion therapy, UR MedicineWilmot Cancer Institute, Part of Jones Memorial Hospital has two locations. Oncologists Neeta Soni, MD, and Yasar Shad, MD provides consultation and treatment for patients at the Olean and in Wellsville locations. The experienced staff has been trained in Wilmot Cancer Institute best practices.. 041b061a72